منابع مشابه
KEGG as a glycome informatics resource.
Bioinformatics approaches to carbohydrate research have recently begun using large amounts of protein and carbohydrate data. In this field called glycome informatics, the foremost necessity is a comprehensive resource for genome-scale bioinformatics analysis of glycan data. Although the accumulation of experimental data may be useful as a reference of biological and biochemical information on c...
متن کاملKEGG as a reference resource for gene and protein annotation
KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an integrated database resource for biological interpretation of genome sequences and other high-throughput data. Molecular functions of genes and proteins are associated with ortholog groups and stored in the KEGG Orthology (KO) database. The KEGG pathway maps, BRITE hierarchies and KEGG modules are developed as networks of KO nodes, ...
متن کاملThe KEGG resource for deciphering the genome
A grand challenge in the post-genomic era is a complete computer representation of the cell and the organism, which will enable computational prediction of higher-level complexity of cellular processes and organism behavior from genomic information. Toward this end we have been developing a knowledge-based approach for network prediction, which is to predict, given a complete set of genes in th...
متن کاملEvaluation of the UMLS as a terminology and knowledge resource for biomedical informatics
OBJECTIVES Terminology and knowledge resources are essential components of interoperability among disparate systems. This paper evaluates whether names and relationships needed in biomedical informatics are present in the UMLS. METHODS Terms for five broad categories of concepts were extracted from LocusLink and mapped to the UMLS Metathesausus. Relationships between gene products and the oth...
متن کاملImaging the glycome.
Molecular imaging enables visualization of specific molecules in vivo and without substantial perturbation to the target molecule's environment. Glycans are appealing targets for molecular imaging but are inaccessible with conventional approaches. Classic methods for monitoring glycans rely on molecular recognition with probe-bearing lectins or antibodies, but these techniques are not well suit...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2006
ISSN: 1460-2423,0959-6658
DOI: 10.1093/glycob/cwj010